Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy

Oncolytic viruses (OVs) are emerging cancer immunotherapy. Despite notable successes in the treatment of some tumors, OV therapy for central nervous system cancers has failed to show efficacy. We used an ex vivo tumor model developed from human glioblastoma tissue to evaluate the infiltration of her...

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Detalles Bibliográficos
Autores principales: Jenner, Adrianne L., Smalley, Munisha, Goldman, David, Goins, William F., Cobbs, Charles S., Puchalski, Ralph B., Chiocca, E. Antonio, Lawler, Sean, Macklin, Paul, Goldman, Aaron, Craig, Morgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142563/
https://www.ncbi.nlm.nih.gov/pubmed/35637733
http://dx.doi.org/10.1016/j.isci.2022.104395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142563/
https://www.ncbi.nlm.nih.gov/pubmed/35637733
http://dx.doi.org/10.1016/j.isci.2022.104395

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