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Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy
Oncolytic viruses (OVs) are emerging cancer immunotherapy. Despite notable successes in the treatment of some tumors, OV therapy for central nervous system cancers has failed to show efficacy. We used an ex vivo tumor model developed from human glioblastoma tissue to evaluate the infiltration of her...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142563/ https://www.ncbi.nlm.nih.gov/pubmed/35637733 http://dx.doi.org/10.1016/j.isci.2022.104395 |