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Proteomic and transcriptomic profiles of human urothelial cancer cells with histone deacetylase 5 overexpression

Urothelial carcinoma (UC) of the urinary bladder is a prevalent cancer worldwide. Because histone deacetylases (HDACs) are important factors in cancer, targeting these epigenetic regulators is considered an attractive strategy to develop novel anticancer drugs. Whereas HDAC1 and HDAC2 promote UC, HD...

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Detalles Bibliográficos
Autores principales: Jaguva Vasudevan, Ananda Ayyappan, Hoffmann, Michèle J., Poschmann, Gereon, Petzsch, Patrick, Wiek, Constanze, Stühler, Kai, Köhrer, Karl, Schulz, Wolfgang A., Niegisch, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142574/
https://www.ncbi.nlm.nih.gov/pubmed/35624179
http://dx.doi.org/10.1038/s41597-022-01319-0