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Fluent molecular mixing of Tau isoforms in Alzheimer’s disease neurofibrillary tangles
Alzheimer’s disease (AD) is defined by intracellular neurofibrillary tangles formed by the microtubule-associated protein tau and extracellular plaques formed by the β-amyloid peptide. AD tau tangles contain a mixture of tau isoforms with either four (4R) or three (3R) microtubule-binding repeats. H...
Autores principales: | Dregni, Aurelio J., Duan, Pu, Xu, Hong, Changolkar, Lakshmi, El Mammeri, Nadia, Lee, Virginia M.-Y., Hong, Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142584/ https://www.ncbi.nlm.nih.gov/pubmed/35624093 http://dx.doi.org/10.1038/s41467-022-30585-0 |
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