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Activation of Nkx2.5 transcriptional program is required for adult myocardial repair

The cardiac developmental network has been associated with myocardial regenerative potential. However, the embryonic signals triggered following injury have yet to be fully elucidated. Nkx2.5 is a key causative transcription factor associated with human congenital heart disease and one of the earlie...

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Detalles Bibliográficos
Autores principales: de Sena-Tomás, Carmen, Aleman, Angelika G., Ford, Caitlin, Varshney, Akriti, Yao, Di, Harrington, Jamie K., Saúde, Leonor, Ramialison, Mirana, Targoff, Kimara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142600/
https://www.ncbi.nlm.nih.gov/pubmed/35624100
http://dx.doi.org/10.1038/s41467-022-30468-4