Ethyl carbamate triggers ferroptosis in liver through inhibiting GSH synthesis and suppressing Nrf2 activation

Humans are inevitably exposed to ethyl carbamate (EC) via consumption of fermented food and beverages. EC, known as an environmental toxin, can cause oxidative stress-mediated severe toxicity, but the underlying mechanisms remain unveiled. Ferroptosis is a newly identified ROS-mediated non-apoptotic...

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Detalles Bibliográficos
Autores principales: Xu, Yang, Li, Yuting, Li, Jiaxin, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142717/
https://www.ncbi.nlm.nih.gov/pubmed/35623314
http://dx.doi.org/10.1016/j.redox.2022.102349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142717/
https://www.ncbi.nlm.nih.gov/pubmed/35623314
http://dx.doi.org/10.1016/j.redox.2022.102349

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