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Efficacy and Safety of FX201, a Novel Intra-Articular IL-1Ra Gene Therapy for Osteoarthritis Treatment, in a Rat Model

Osteoarthritis (OA) is a disabling, degenerative disease characterized by progressive cartilage and bone damage. There remains a need for local therapies that, following a single injection, can provide long-term pain relief and functional improvement and potentially delay disease progression. FX201...

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Detalles Bibliográficos
Autores principales: Senter, Rebecca, Boyce, Rogely, Repic, Marko, Martin, Emily Walsh, Chabicovsky, Monika, Langevin-Carpentier, Geneviève, Bédard, Agathe, Bodick, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142767/
https://www.ncbi.nlm.nih.gov/pubmed/34963343
http://dx.doi.org/10.1089/hum.2021.131