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Unusual increase in carcinoembryonic antigen despite response to selpercatinib in two patients with medullary thyroid cancer

INTRODUCTION: Serum calcitonin (CT) and carcinoembryonic antigen (CEA) are valuable tumour markers in patients with medullary thyroid carcinoma (MTC). Both markers most often evolve in parallel after treatment. Selpercatinib (LOXO-292) is a highly selective RET kinase inhibitor indicated in advanced...

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Detalles Bibliográficos
Autores principales: Bardet, Stéphane, Ciappuccini, Renaud, Lamartina, Livia, Leboulleux, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142795/
https://www.ncbi.nlm.nih.gov/pubmed/35007206
http://dx.doi.org/10.1530/ETJ-21-0104