Inflammation and serotonin deficiency in major depressive disorder: molecular docking of antidepressant and anti-inflammatory drugs to tryptophan and indoleamine 2,3-dioxygenases

The roles of the kynurenine pathway (KP) of tryptophan (Trp) degradation in serotonin deficiency in major depressive disorder (MDD) and the associated inflammatory state are considered in the present study. Using molecular docking in silico, we demonstrate binding of antidepressants to the crystal s...

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Detalles Bibliográficos
Autores principales: Dawood, Shazia, Bano, Samina, Badawy, Abdulla A.-B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Biochemical Techniques & Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142829/
https://www.ncbi.nlm.nih.gov/pubmed/35506370
http://dx.doi.org/10.1042/BSR20220426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142829/
https://www.ncbi.nlm.nih.gov/pubmed/35506370
http://dx.doi.org/10.1042/BSR20220426

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