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Carbonic Anhydrase IX-Targeted α-Radionuclide Therapy with 225Ac Inhibits Tumor Growth in a Renal Cell Carcinoma Model
In this study, we compared the tumor-targeting properties, therapeutic efficacy, and tolerability of the humanized anti-CAIX antibody (hG250) labeled with either the α-emitter actinium-225 ((225)Ac) or the β(-)-emitter lutetium-177 ((177)Lu) in mice. BALB/c nude mice were grafted with human renal ce...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142961/ https://www.ncbi.nlm.nih.gov/pubmed/35631396 http://dx.doi.org/10.3390/ph15050570 |