Antioxidant Properties and Aldehyde Reactivity of PD-L1 Targeted Aryl-Pyrazolone Anticancer Agents

Small molecules targeting the PD-1/PD-L1 checkpoint are actively searched to complement the anticancer arsenal. Different molecular scaffolds have been reported, including phenyl-pyrazolone derivatives which potently inhibit binding of PD-L1 to PD-1. These molecules are structurally close to antioxi...

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Detalles Bibliográficos
Autores principales: Leleu-Chavain, Natascha, Regnault, Romain, Ahouari, Hania, Le Biannic, Raphaël, Kouach, Mostafa, Klupsch, Frédérique, Magnez, Romain, Vezin, Hervé, Thuru, Xavier, Bailly, Christian, Goossens, Jean-François, Millet, Régis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143004/
https://www.ncbi.nlm.nih.gov/pubmed/35630791
http://dx.doi.org/10.3390/molecules27103316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143004/
https://www.ncbi.nlm.nih.gov/pubmed/35630791
http://dx.doi.org/10.3390/molecules27103316

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