Chitosan-Hyaluronan Nanoparticles for Vinblastine Sulfate Delivery: Characterization and Internalization Studies on K-562 Cells

In the present study, we developed chitosan/hyaluronan nanoparticles (CS/HY NPs) for tumor targeting with vinblastine sulfate (VBL), that can be directed to the CD44 transmembrane receptor, over-expressed in cancer cells. NPs were prepared by coating with HY-preformed chitosan/tripolyphosphate (CS/T...

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Detalles Bibliográficos
Autores principales: Cannavà, Carmela, De Gaetano, Federica, Stancanelli, Rosanna, Venuti, Valentina, Paladini, Giuseppe, Caridi, Francesco, Ghica, Corneliu, Crupi, Vincenza, Majolino, Domenico, Ferlazzo, Guido, Tommasini, Silvana, Ventura, Cinzia Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143110/
https://www.ncbi.nlm.nih.gov/pubmed/35631528
http://dx.doi.org/10.3390/pharmaceutics14050942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143110/
https://www.ncbi.nlm.nih.gov/pubmed/35631528
http://dx.doi.org/10.3390/pharmaceutics14050942

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