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HDAC Inhibitors Enhance Efficacy of the Oncolytic Adenoviruses Ad∆∆ and Ad-3∆-A20T in Pancreatic and Triple-Negative Breast Cancer Models

The prognosis for triple-negative breast cancer (TNBC) and pancreatic ductal adenocarcinoma (PDAC) is dismal. TNBC and PDAC are highly aggressive cancers with few treatment options and a potential for rapid resistance to standard-of-care chemotherapeutics. Oncolytic adenoviruses (OAds) represent a p...

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Detalles Bibliográficos
Autores principales: Rodríguez, María Del Carmen Rodríguez, Rodríguez, Inés García, Nattress, Callum, Qureshi, Ahad, Halldén, Gunnel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143155/
https://www.ncbi.nlm.nih.gov/pubmed/35632748
http://dx.doi.org/10.3390/v14051006