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Poly (N-Vinylcaprolactam-Grafted-Sodium Alginate) Based Injectable pH/Thermo Responsive In Situ Forming Depot Hydrogels for Prolonged Controlled Anticancer Drug Delivery; In Vitro, In Vivo Characterization and Toxicity Evaluation

This study was aimed to develop novel in situ forming gels based on N-vinylcaprolactam, sodium alginate, and N,N-methylenebisacrylamide. The in situ Poly (NVRCL-g-NaAlg) gels were developed using the cold and free radical polymerization method. The structure formation, thermal stability, and porous...

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Detalles Bibliográficos
Autores principales: Khan, Samiullah, Minhas, Muhammad Usman, Aqeel, Muhammad Tahir, Shah, Ihsan, Khan, Shahzeb, Kazi, Mohsin, Warnken, Zachary N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143242/
https://www.ncbi.nlm.nih.gov/pubmed/35631636
http://dx.doi.org/10.3390/pharmaceutics14051050