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Poly (N-Vinylcaprolactam-Grafted-Sodium Alginate) Based Injectable pH/Thermo Responsive In Situ Forming Depot Hydrogels for Prolonged Controlled Anticancer Drug Delivery; In Vitro, In Vivo Characterization and Toxicity Evaluation
This study was aimed to develop novel in situ forming gels based on N-vinylcaprolactam, sodium alginate, and N,N-methylenebisacrylamide. The in situ Poly (NVRCL-g-NaAlg) gels were developed using the cold and free radical polymerization method. The structure formation, thermal stability, and porous...
Autores principales: | Khan, Samiullah, Minhas, Muhammad Usman, Aqeel, Muhammad Tahir, Shah, Ihsan, Khan, Shahzeb, Kazi, Mohsin, Warnken, Zachary N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143242/ https://www.ncbi.nlm.nih.gov/pubmed/35631636 http://dx.doi.org/10.3390/pharmaceutics14051050 |
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