[(99m)Tc]Tc-iFAP Radioligand for SPECT/CT Imaging of the Tumor Microenvironment: Kinetics, Radiation Dosimetry, and Imaging in Patients

Tumor microenvironment fibroblasts overexpress the fibroblast activation protein (FAP). We recently reported the preclinical evaluation of [(99m)Tc]Tc-iFAP as a new SPECT radioligand capable of detecting FAP. This research aimed to evaluate the kinetic and dosimetric profile of [(99m)Tc]Tc-iFAP in h...

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Detalles Bibliográficos
Autores principales: Coria-Domínguez, Luis, Vallejo-Armenta, Paola, Luna-Gutiérrez, Myrna, Ocampo-García, Blanca, Gibbens-Bandala, Brenda, García-Pérez, Francisco, Ramírez-Nava, Gerardo, Santos-Cuevas, Clara, Ferro-Flores, Guillermina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143259/
https://www.ncbi.nlm.nih.gov/pubmed/35631416
http://dx.doi.org/10.3390/ph15050590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143259/
https://www.ncbi.nlm.nih.gov/pubmed/35631416
http://dx.doi.org/10.3390/ph15050590

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