Cargando…
[(99m)Tc]Tc-iFAP Radioligand for SPECT/CT Imaging of the Tumor Microenvironment: Kinetics, Radiation Dosimetry, and Imaging in Patients
Tumor microenvironment fibroblasts overexpress the fibroblast activation protein (FAP). We recently reported the preclinical evaluation of [(99m)Tc]Tc-iFAP as a new SPECT radioligand capable of detecting FAP. This research aimed to evaluate the kinetic and dosimetric profile of [(99m)Tc]Tc-iFAP in h...
Autores principales: | Coria-Domínguez, Luis, Vallejo-Armenta, Paola, Luna-Gutiérrez, Myrna, Ocampo-García, Blanca, Gibbens-Bandala, Brenda, García-Pérez, Francisco, Ramírez-Nava, Gerardo, Santos-Cuevas, Clara, Ferro-Flores, Guillermina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143259/ https://www.ncbi.nlm.nih.gov/pubmed/35631416 http://dx.doi.org/10.3390/ph15050590 |
Ejemplares similares
-
[(99m)Tc]Tc-iFAP/SPECT Tumor Stroma Imaging: Acquisition and Analysis of Clinical Images in Six Different Cancer Entities
por: Vallejo-Armenta, Paola, et al.
Publicado: (2022) -
Design, Synthesis and Preclinical Assessment of (99m)Tc-iFAP for In Vivo Fibroblast Activation Protein (FAP) Imaging
por: Trujillo-Benítez, Diana, et al.
Publicado: (2022) -
Toxicity Assessment of [(177)Lu]Lu−iFAP/iPSMA Nanoparticles Prepared under GMP-Compliant Radiopharmaceutical Processes
por: Hernández-Jiménez, Tania, et al.
Publicado: (2022) -
Targeted Endoradiotherapy with Lu(2)O(3)-iPSMA/-iFAP Nanoparticles Activated by Neutron Irradiation: Preclinical Evaluation and First Patient Image
por: Luna-Gutiérrez, Myrna, et al.
Publicado: (2022) -
(99m)Tc-CXCR4-L for Imaging of the Chemokine-4 Receptor Associated with Brain Tumor Invasiveness: Biokinetics, Radiation Dosimetry, and Proof of Concept in Humans
por: Vallejo-Armenta, Paola, et al.
Publicado: (2020)