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Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma

We previously reported the remarkable potency of uttroside B (Utt-B), saponin-isolated and characterized in our lab from Solanum nigrum Linn, against HCC. Recently, the U.S. FDA approved Utt-B as an ‘orphan drug’ against HCC. The current study validates the superior anti-HCC efficacy of Utt-B over s...

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Detalles Bibliográficos
Autores principales: Swetha, Mundanattu, Keerthana, Chenicheri K., Rayginia, Tennyson P., Nath, Lekshmi R., Haritha, Nair Hariprasad, Shabna, Anwar, Kalimuthu, Kalishwaralal, Thangarasu, Arun K., Aiswarya, Sreekumar U., Jannet, Somaraj, Pillai, Sreekumar, Harikumar, Kuzhuvelil B., Sundaram, Sankar, Anto, Nikhil Ponnoor, Wu, Dee H., Lankalapalli, Ravi S., Towner, Rheal, Isakov, Noah, Deepa, Sathyaseelan S., Anto, Ruby John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143354/
https://www.ncbi.nlm.nih.gov/pubmed/35631464
http://dx.doi.org/10.3390/ph15050636