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Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma
We previously reported the remarkable potency of uttroside B (Utt-B), saponin-isolated and characterized in our lab from Solanum nigrum Linn, against HCC. Recently, the U.S. FDA approved Utt-B as an ‘orphan drug’ against HCC. The current study validates the superior anti-HCC efficacy of Utt-B over s...
Autores principales: | Swetha, Mundanattu, Keerthana, Chenicheri K., Rayginia, Tennyson P., Nath, Lekshmi R., Haritha, Nair Hariprasad, Shabna, Anwar, Kalimuthu, Kalishwaralal, Thangarasu, Arun K., Aiswarya, Sreekumar U., Jannet, Somaraj, Pillai, Sreekumar, Harikumar, Kuzhuvelil B., Sundaram, Sankar, Anto, Nikhil Ponnoor, Wu, Dee H., Lankalapalli, Ravi S., Towner, Rheal, Isakov, Noah, Deepa, Sathyaseelan S., Anto, Ruby John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143354/ https://www.ncbi.nlm.nih.gov/pubmed/35631464 http://dx.doi.org/10.3390/ph15050636 |
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