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Combinatorial Metabolic Engineering and Enzymatic Catalysis Enable Efficient Production of Colanic Acid

Colanic acid can promote the lifespan of humans by regulating mitochondrial homeostasis, and it has widespread applications in the field of health. However, colanic acid is produced at a low temperature (20 °C) with low titer. Using Escherichia coli K-12 MG1655, we constructed the SRP-4 strain with...

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Detalles Bibliográficos
Autores principales: Li, Suwei, Xu, Xianhao, Lv, Xueqin, Liu, Yanfeng, Li, Jianghua, Du, Guocheng, Liu, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143390/
https://www.ncbi.nlm.nih.gov/pubmed/35630322
http://dx.doi.org/10.3390/microorganisms10050877