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Combinatorial Metabolic Engineering and Enzymatic Catalysis Enable Efficient Production of Colanic Acid
Colanic acid can promote the lifespan of humans by regulating mitochondrial homeostasis, and it has widespread applications in the field of health. However, colanic acid is produced at a low temperature (20 °C) with low titer. Using Escherichia coli K-12 MG1655, we constructed the SRP-4 strain with...
Autores principales: | Li, Suwei, Xu, Xianhao, Lv, Xueqin, Liu, Yanfeng, Li, Jianghua, Du, Guocheng, Liu, Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143390/ https://www.ncbi.nlm.nih.gov/pubmed/35630322 http://dx.doi.org/10.3390/microorganisms10050877 |
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