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Ionizable Lipid Nanoparticles Enhanced the Synergistic Adjuvant Effect of CpG ODNs and QS21 in a Varicella Zoster Virus Glycoprotein E Subunit Vaccine

Varicella zoster virus (VZV) causes two diseases: varicella upon primary infection and herpes zoster when latent viruses in the sensory ganglia reactivate. While varicella vaccines depend on humoral immunity to prevent VZV infection, cell-mediated immunity (CMI), which plays a therapeutic role in th...

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Detalles Bibliográficos
Autores principales: Luan, Ning, Cao, Han, Wang, Yunfei, Lin, Kangyang, Liu, Cunbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143440/
https://www.ncbi.nlm.nih.gov/pubmed/35631559
http://dx.doi.org/10.3390/pharmaceutics14050973