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In Vitro CRISPR/Cas9 Transfection and Gene-Editing Mediated by Multivalent Cationic Liposome–DNA Complexes

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated nuclease 9 (Cas9) gene-editing offers exciting new therapeutic possibilities for disease treatment with a genetic etiology such as cancer, cardiovascular, neuronal, and immune disorders. However, its clinical tr...

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Detalles Bibliográficos
Autores principales: Sousa, Diana A., Gaspar, Ricardo, Ferreira, Celso J. O., Baltazar, Fátima, Rodrigues, Ligia R., Silva, Bruno F. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143451/
https://www.ncbi.nlm.nih.gov/pubmed/35631673
http://dx.doi.org/10.3390/pharmaceutics14051087