Frequency of CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism in a Spanish Population: Linkage Disequilibrium with CYP2C9*3 Allele

Background: A promoter variable number tandem repeat polymorphism (pVNTR) of CYP2C9 is described with three types of fragments: short (pVNTR-S), medium (pVNTR-M) and long (pVNTR-L). The pVNTR-S allele reduces the CYP2C9 mRNA level in the human liver, and it was found to be in high linkage disequilib...

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Detalles Bibliográficos
Autores principales: Dorado, Pedro, Santos-Díaz, Gracia, Gutiérrez-Martín, Yolanda, Suárez-Santisteban, Miguel Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143480/
https://www.ncbi.nlm.nih.gov/pubmed/35629204
http://dx.doi.org/10.3390/jpm12050782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143480/
https://www.ncbi.nlm.nih.gov/pubmed/35629204
http://dx.doi.org/10.3390/jpm12050782

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