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Frequency of CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism in a Spanish Population: Linkage Disequilibrium with CYP2C9*3 Allele
Background: A promoter variable number tandem repeat polymorphism (pVNTR) of CYP2C9 is described with three types of fragments: short (pVNTR-S), medium (pVNTR-M) and long (pVNTR-L). The pVNTR-S allele reduces the CYP2C9 mRNA level in the human liver, and it was found to be in high linkage disequilib...
Autores principales: | Dorado, Pedro, Santos-Díaz, Gracia, Gutiérrez-Martín, Yolanda, Suárez-Santisteban, Miguel Ángel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143480/ https://www.ncbi.nlm.nih.gov/pubmed/35629204 http://dx.doi.org/10.3390/jpm12050782 |
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