Investigating the Mechanisms behind the Positive Food Effect of Abiraterone Acetate: In Vitro and Rat In Situ Studies

The anticancer agent abiraterone suffers from an extensive positive food effect after oral intake of the prodrug abiraterone acetate (Zytiga). The underlying processes determining postprandial abiraterone absorption were investigated in this study. The impact of lipids and lipid digestion products o...

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Detalles Bibliográficos
Autores principales: Braeckmans, Marlies, Augustijns, Patrick, Mols, Raf, Servais, Cécile, Brouwers, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143506/
https://www.ncbi.nlm.nih.gov/pubmed/35631538
http://dx.doi.org/10.3390/pharmaceutics14050952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143506/
https://www.ncbi.nlm.nih.gov/pubmed/35631538
http://dx.doi.org/10.3390/pharmaceutics14050952

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