Integrin/TGF-β1 Inhibitor GLPG-0187 Blocks SARS-CoV-2 Delta and Omicron Pseudovirus Infection of Airway Epithelial Cells In Vitro, Which Could Attenuate Disease Severity

As COVID-19 continues to pose major risk for vulnerable populations, including the elderly, immunocompromised, patients with cancer, and those with contraindications to vaccination, novel treatment strategies are urgently needed. SARS-CoV-2 infects target cells via RGD-binding integrins, either inde...

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Detalles Bibliográficos
Autores principales: Huntington, Kelsey E., Carlsen, Lindsey, So, Eui-Young, Piesche, Matthias, Liang, Olin, El-Deiry, Wafik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143518/
https://www.ncbi.nlm.nih.gov/pubmed/35631444
http://dx.doi.org/10.3390/ph15050618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143518/
https://www.ncbi.nlm.nih.gov/pubmed/35631444
http://dx.doi.org/10.3390/ph15050618

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