DNA Conformational Changes Induced by Its Interaction with Binuclear Platinum Complexes in Solution Indicate the Molecular Mechanism of Platinum Binding

Platinum anticancer drugs inhibit the division of cancer cells through a DNA binding mechanism. The bimetallic platinum compounds have a possibility for blocking DNA replication via the cross-linking of DNA functional groups at different distances. Many compounds with metals of the platinum group ha...

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Detalles Bibliográficos
Autores principales: Kasyanenko, Nina, Qiushi, Zhang, Bakulev, Vladimir, Sokolov, Petr, Yakovlev, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143540/
https://www.ncbi.nlm.nih.gov/pubmed/35631926
http://dx.doi.org/10.3390/polym14102044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143540/
https://www.ncbi.nlm.nih.gov/pubmed/35631926
http://dx.doi.org/10.3390/polym14102044

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