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Immune Responses Induced by Recombinant Bacillus subtilis Expressing the PEDV Spike Protein Targeted at Microfold Cells

Bacillus subtilis (B. subtilis), a probiotic bacterium and feeding additive, is widely used for heterologous antigen expression and protective immunisation. Porcine epidemic diarrhoea virus (PEDV) invades swine via mucosal tissue. To enhance the mucosal immune response to PEDV, we modified B. subtil...

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Detalles Bibliográficos
Autores principales: Lin, Jian, Mou, Chunxiao, Zhang, Shuai, Zhu, Liqi, Li, Yuchen, Yang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143571/
https://www.ncbi.nlm.nih.gov/pubmed/35622739
http://dx.doi.org/10.3390/vetsci9050211