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Immune Responses Induced by Recombinant Bacillus subtilis Expressing the PEDV Spike Protein Targeted at Microfold Cells
Bacillus subtilis (B. subtilis), a probiotic bacterium and feeding additive, is widely used for heterologous antigen expression and protective immunisation. Porcine epidemic diarrhoea virus (PEDV) invades swine via mucosal tissue. To enhance the mucosal immune response to PEDV, we modified B. subtil...
Autores principales: | Lin, Jian, Mou, Chunxiao, Zhang, Shuai, Zhu, Liqi, Li, Yuchen, Yang, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143571/ https://www.ncbi.nlm.nih.gov/pubmed/35622739 http://dx.doi.org/10.3390/vetsci9050211 |
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