Cationic Geminoid Peptide Amphiphiles Inhibit DENV2 Protease, Furin, and Viral Replication

Dengue is an important arboviral infectious disease for which there is currently no specific cure. We report gemini-like (geminoid) alkylated amphiphilic peptides containing lysines in combination with glycines or alanines (C(15)H(31)C(O)-Lys-(Gly or Ala)(n)Lys-NHC(16)H(33), shorthand notation C(16)...

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Detalles Bibliográficos
Autores principales: Damen, Mark, Izidoro, Mario A., Okamoto, Debora N., Oliveira, Lilian C. G., Amatdjais-Groenen, Helene I. V., van Dongen, Stijn F. M., van Cleef, Koen W. R., van Rij, Ronald P., Dieteren, Cindy E. J., Gironés, Daniel, van Buuren, Bernd N. M., Martina, Byron E. E., Osterhaus, Albert D. M. E., Juliano, Luiz, Scholte, Bob J., Feiters, Martin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143577/
https://www.ncbi.nlm.nih.gov/pubmed/35630694
http://dx.doi.org/10.3390/molecules27103217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143577/
https://www.ncbi.nlm.nih.gov/pubmed/35630694
http://dx.doi.org/10.3390/molecules27103217

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