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Biodistribution of Intra-Arterial and Intravenous Delivery of Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles in a Rat Model to Guide Delivery Strategies for Diabetes Therapies

Umbilical cord mesenchymal stem cell-derived extracellular vesicles (UC-MSC-EVs) have become an emerging strategy for treating various autoimmune and metabolic disorders, particularly diabetes. Delivery of UC-MSC-EVs is essential to ensure optimal efficacy of UC-MSC-EVs. To develop safe and superior...

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Detalles Bibliográficos
Autores principales: Li, Junfeng, Komatsu, Hirotake, Poku, Erasmus K., Olafsen, Tove, Huang, Kelly X., Huang, Lina A., Chea, Junie, Bowles, Nicole, Chang, Betty, Rawson, Jeffrey, Peng, Jiangling, Wu, Anna M., Shively, John E., Kandeel, Fouad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143655/
https://www.ncbi.nlm.nih.gov/pubmed/35631421
http://dx.doi.org/10.3390/ph15050595