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Identification of Asiaticoside from Centella erecta (Apiaceae) as Potential Apyrase Inhibitor by UF-UHPLC-MS and Its In Vivo Antischistosomal Activity

Schistosomiasis, caused by parasites of the genus Schistosoma, is a neglected disease with high global prevalence, affecting more than 240 million people in several countries. Praziquantel (PZQ) is the only drug currently available for the treatment. S. mansoni NTPDases (known as SmNTPDases, ATP dip...

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Detalles Bibliográficos
Autores principales: de Carvalho, Lara Soares Aleixo, de Souza, Vinícius Carius, Rodrigues, Vinícius C., Ribeiro, Aline Correa, Nascimento, Jorge Willian Leandro, Capriles, Priscila V. S. Z., Pinto, Priscila de F., de Moraes, Josué, da Silva Filho, Ademar Alves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143675/
https://www.ncbi.nlm.nih.gov/pubmed/35631657
http://dx.doi.org/10.3390/pharmaceutics14051071