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Identification of Asiaticoside from Centella erecta (Apiaceae) as Potential Apyrase Inhibitor by UF-UHPLC-MS and Its In Vivo Antischistosomal Activity
Schistosomiasis, caused by parasites of the genus Schistosoma, is a neglected disease with high global prevalence, affecting more than 240 million people in several countries. Praziquantel (PZQ) is the only drug currently available for the treatment. S. mansoni NTPDases (known as SmNTPDases, ATP dip...
Autores principales: | de Carvalho, Lara Soares Aleixo, de Souza, Vinícius Carius, Rodrigues, Vinícius C., Ribeiro, Aline Correa, Nascimento, Jorge Willian Leandro, Capriles, Priscila V. S. Z., Pinto, Priscila de F., de Moraes, Josué, da Silva Filho, Ademar Alves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143675/ https://www.ncbi.nlm.nih.gov/pubmed/35631657 http://dx.doi.org/10.3390/pharmaceutics14051071 |
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