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Adipose Tissue Secretion Pattern Influences β-Cell Wellness in the Transition from Obesity to Type 2 Diabetes

The dysregulation of the β-cell functional mass, which is a reduction in the number of β-cells and their ability to secure adequate insulin secretion, represents a key mechanistic factor leading to the onset of type 2 diabetes (T2D). Obesity is recognised as a leading cause of β-cell loss and dysfun...

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Detalles Bibliográficos
Autores principales: Biondi, Giuseppina, Marrano, Nicola, Borrelli, Anna, Rella, Martina, Palma, Giuseppe, Calderoni, Isabella, Siciliano, Edoardo, Lops, Pasquale, Giorgino, Francesco, Natalicchio, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143684/
https://www.ncbi.nlm.nih.gov/pubmed/35628332
http://dx.doi.org/10.3390/ijms23105522