Reduced the Food Effect and Enhanced the Oral Bioavailability of Ivacaftor by Self-Nanoemulsifying Drug Delivery System (SNEDDS) Using a New Oil Phase

PURPOSE: The purpose of this work was to develop an ivacaftor self-nanoemulsion drug delivery system (IVA-SNEDDS) using the newly developed double headed miscellaneous lipid (DHML) as oil phase to reduce the food effect and inter-individual absorption variability of IVA. METHODS: The lipids with the...

Descripción completa

Detalles Bibliográficos
Autores principales: Miao, Yanfei, Zhao, Shihua, Zuo, Jian, Sun, Jiqin, Wang, Jingnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143795/
https://www.ncbi.nlm.nih.gov/pubmed/35637746
http://dx.doi.org/10.2147/DDDT.S356967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143795/
https://www.ncbi.nlm.nih.gov/pubmed/35637746
http://dx.doi.org/10.2147/DDDT.S356967

Ejemplares similares