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Reduced the Food Effect and Enhanced the Oral Bioavailability of Ivacaftor by Self-Nanoemulsifying Drug Delivery System (SNEDDS) Using a New Oil Phase

PURPOSE: The purpose of this work was to develop an ivacaftor self-nanoemulsion drug delivery system (IVA-SNEDDS) using the newly developed double headed miscellaneous lipid (DHML) as oil phase to reduce the food effect and inter-individual absorption variability of IVA. METHODS: The lipids with the...

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Detalles Bibliográficos
Autores principales:	Miao, Yanfei, Zhao, Shihua, Zuo, Jian, Sun, Jiqin, Wang, Jingnan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143795/ https://www.ncbi.nlm.nih.gov/pubmed/35637746 http://dx.doi.org/10.2147/DDDT.S356967

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