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Isotopic Radiolabeling of the Antiretroviral Drug [(18)F]Dolutegravir for Pharmacokinetic PET Imaging

Deciphering the drug/virus/host interactions at infected cell reservoirs is a key leading to HIV-1 remission for which positron emission tomography (PET) imaging using radiolabeled antiretroviral (ARV) drugs is a powerful asset. Dolutegravir (DTG) is one of the preferred therapeutic options to treat...

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Detalles Bibliográficos
Autores principales: Tisseraud, Marion, Goutal, Sébastien, Bonasera, Thomas, Goislard, Maud, Desjardins, Delphine, Le Grand, Roger, Parry, Chris M., Tournier, Nicolas, Kuhnast, Bertrand, Caillé, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143889/
https://www.ncbi.nlm.nih.gov/pubmed/35631413
http://dx.doi.org/10.3390/ph15050587