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β-Elemene Attenuates Renal Fibrosis in the Unilateral Ureteral Obstruction Model by Inhibition of STAT3 and Smad3 Signaling via Suppressing MyD88 Expression

Renal fibrosis is a chronic pathological process that seriously endangers human health. However, the current therapeutic options for this disease are extremely limited. Previous studies have shown that signaling factors such as JAK2/STAT3, Smad3, and Myd88 play a regulatory role in renal fibrosis, a...

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Detalles Bibliográficos
Autores principales: Sun, Wenjuan, Kim, Dong Hyun, Byon, Chang Hyun, Choi, Hoon In, Park, Jung Sun, Bae, Eun Hui, Ma, Seong Kwon, Kim, Soo Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9143890/
https://www.ncbi.nlm.nih.gov/pubmed/35628363
http://dx.doi.org/10.3390/ijms23105553