Phosphorylation at Ser(724) of the ER stress sensor IRE1α governs its activation state and limits ER stress–induced hepatosteatosis

Inositol-requiring enzyme 1 (IRE1) is an evolutionarily conserved sensor of endoplasmic reticulum (ER) stress and mediates a key branch of the unfolded protein response in eukaryotic cells. It is an ER-resident transmembrane protein that possesses Ser/Thr protein kinase and endoribonuclease (RNase)...

詳細記述

書誌詳細
主要な著者: Li, Yang, Huang, Shijia, Wang, Jingsi, Dai, Jianli, Cai, Jie, Yan, Shuai, Huang, Zhiliang, He, Shengqi, Wang, Ping, Liu, Jianmiao, Liu, Yong
フォーマット: Online 論文 テキスト
言語:English
出版事項: American Society for Biochemistry and Molecular Biology 2022
主題:
Research Article
オンライン･アクセス:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144033/
https://www.ncbi.nlm.nih.gov/pubmed/35500653
http://dx.doi.org/10.1016/j.jbc.2022.101997

インターネット

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144033/
https://www.ncbi.nlm.nih.gov/pubmed/35500653
http://dx.doi.org/10.1016/j.jbc.2022.101997

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