Spontaneous DNA Synapsis by Forming Noncanonical Intermolecular Structures

We report the spontaneous formation of DNA-DNA junctions in solution in the absence of proteins visualised using atomic force microscopy. The synapsis position fits with potential G-quadruplex (G4) sites. In contrast to the Holliday structure, these conjugates have an affinity for G4 antibodies. Mol...

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Detalles Bibliográficos
Autores principales: Severov, Viacheslav, Tsvetkov, Vladimir, Barinov, Nikolay, Babenko, Vladislav, Klinov, Dmitry, Pozmogova, Galina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144187/
https://www.ncbi.nlm.nih.gov/pubmed/35632001
http://dx.doi.org/10.3390/polym14102118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144187/
https://www.ncbi.nlm.nih.gov/pubmed/35632001
http://dx.doi.org/10.3390/polym14102118

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