Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia

Statins are the first-line treatment for familial hypercholesterolemia (FH), but response is highly variable due to genetic and nongenetic factors. Here, we explored the association between response and genetic variability in 114 Brazilian adult FH patients. Specifically, a panel of 84 genes was ana...

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Detalles Bibliográficos
Autores principales: Dagli-Hernandez, Carolina, Borges, Jéssica Bassani, Marçal, Elisangela da Silva Rodrigues, de Freitas, Renata Caroline Costa, Mori, Augusto Akira, Gonçalves, Rodrigo Marques, Faludi, Andre Arpad, de Oliveira, Victor Fernandes, Ferreira, Glaucio Monteiro, Bastos, Gisele Medeiros, Zhou, Yitian, Lauschke, Volker M., Cerda, Alvaro, Hirata, Mario Hiroyuki, Hirata, Rosario Dominguez Crespo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144204/
https://www.ncbi.nlm.nih.gov/pubmed/35631530
http://dx.doi.org/10.3390/pharmaceutics14050944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144204/
https://www.ncbi.nlm.nih.gov/pubmed/35631530
http://dx.doi.org/10.3390/pharmaceutics14050944

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