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Synthesis, Biological Activity, and Molecular Modelling Studies of Naphthoquinone Derivatives as Promising Anticancer Candidates Targeting COX-2

Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-associated mortalities worldwide. Therefore, it is crucial to develop a novel therapeutic option targeting localized and metastatic NSCLC. In this paper, we describe the synthesis and biological activity characterization of naphtho...

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Detalles Bibliográficos
Autores principales: Kavaliauskas, Povilas, Opazo, Felipe Stambuk, Acevedo, Waldo, Petraitiene, Ruta, Grybaitė, Birutė, Anusevičius, Kazimieras, Mickevičius, Vytautas, Belyakov, Sergey, Petraitis, Vidmantas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144205/
https://www.ncbi.nlm.nih.gov/pubmed/35631366
http://dx.doi.org/10.3390/ph15050541