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A Single Injection of NTG-101 Reduces the Expression of Pain-Related Neurotrophins in a Canine Model of Degenerative Disc Disease

Background: Tissue sources of pain emanating from degenerative discs remains incompletely understood. Canine intervertebral discs (IVDs) were needle puncture injured, 4-weeks later injected with either phosphate-buffered saline (PBS) or NTG-101, harvested after an additional fourteen weeks and then...

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Detalles Bibliográficos
Autores principales: Matta, Ajay, Karim, Muhammad Zia, Gerami, Hoda, Benigno, Bettina Zoe, Cheng, Ivan, Mehrkens, Arne, Erwin, William Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144207/
https://www.ncbi.nlm.nih.gov/pubmed/35628530
http://dx.doi.org/10.3390/ijms23105717