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Epithelial Sodium Channel Inhibition by Amiloride Addressed with THz Spectroscopy and Molecular Modeling

THz spectroscopy is important for the study of ion channels because it directly addresses the low frequency collective motions relevant for their function. Here we used THz spectroscopy to investigate the inhibition of the epithelial sodium channel (ENaC) by its specific blocker, amiloride. Experime...

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Detalles Bibliográficos
Autores principales: Mernea, Maria, Ulăreanu, Roxana Ștefania, Cucu, Dana, Al-Saedi, Jasim Hafedh, Pop, Cristian-Emilian, Fendrihan, Sergiu, Anghelescu, Giorgiana Diana Carmen, Mihăilescu, Dan Florin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144217/
https://www.ncbi.nlm.nih.gov/pubmed/35630748
http://dx.doi.org/10.3390/molecules27103271