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Crassolide Induces G2/M Cell Cycle Arrest, Apoptosis, and Autophagy in Human Lung Cancer Cells via ROS-Mediated ER Stress Pathways

Crassolide, a cembranoid diterpene extracted from the soft coral Lobophytum crissum, has been proven to possess antioxidant and immunomodulatory properties. In the present study, we assessed the anticancer effects of crassolide on human H460 non-small-cell lung cancer (NSCLC) cells. We found that cr...

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Detalles Bibliográficos
Autores principales: Lai, Kuan-Ming, Wang, Jou-Hsuan, Lin, Shih-Chao, Wen, Ya, Wu, Chao-Liang, Su, Jui-Hsin, Chen, Chien-Chin, Lin, Chi-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144222/
https://www.ncbi.nlm.nih.gov/pubmed/35628435
http://dx.doi.org/10.3390/ijms23105624