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Crassolide Induces G2/M Cell Cycle Arrest, Apoptosis, and Autophagy in Human Lung Cancer Cells via ROS-Mediated ER Stress Pathways
Crassolide, a cembranoid diterpene extracted from the soft coral Lobophytum crissum, has been proven to possess antioxidant and immunomodulatory properties. In the present study, we assessed the anticancer effects of crassolide on human H460 non-small-cell lung cancer (NSCLC) cells. We found that cr...
Autores principales: | Lai, Kuan-Ming, Wang, Jou-Hsuan, Lin, Shih-Chao, Wen, Ya, Wu, Chao-Liang, Su, Jui-Hsin, Chen, Chien-Chin, Lin, Chi-Chien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144222/ https://www.ncbi.nlm.nih.gov/pubmed/35628435 http://dx.doi.org/10.3390/ijms23105624 |
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