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Poloxamer 407/188 Binary Thermosensitive Gel as a Moxidectin Delivery System: In Vitro Release and In Vivo Evaluation

Moxidectin (MXD) is an antiparasitic drug used extensively in veterinary clinics. In this study, to develop a new formulation of MXD, a thermosensitive gel of MXD (MXD-TG) was prepared based on poloxamer 407/188. Furthermore, the gelation temperature, the stability, in vitro release kinetics and in...

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Detalles Bibliográficos
Autores principales: Ruan, Xiangchun, Hu, Jidong, Lu, Lianshou, Wang, Youwei, Tang, Chunlian, Liu, Faquan, Gao, Xiuge, Zhang, Li, Wu, Hao, Huang, Xianhui, Wei, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144259/
https://www.ncbi.nlm.nih.gov/pubmed/35630537
http://dx.doi.org/10.3390/molecules27103063