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Poloxamer 407/188 Binary Thermosensitive Gel as a Moxidectin Delivery System: In Vitro Release and In Vivo Evaluation
Moxidectin (MXD) is an antiparasitic drug used extensively in veterinary clinics. In this study, to develop a new formulation of MXD, a thermosensitive gel of MXD (MXD-TG) was prepared based on poloxamer 407/188. Furthermore, the gelation temperature, the stability, in vitro release kinetics and in...
Autores principales: | Ruan, Xiangchun, Hu, Jidong, Lu, Lianshou, Wang, Youwei, Tang, Chunlian, Liu, Faquan, Gao, Xiuge, Zhang, Li, Wu, Hao, Huang, Xianhui, Wei, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144259/ https://www.ncbi.nlm.nih.gov/pubmed/35630537 http://dx.doi.org/10.3390/molecules27103063 |
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