Analysis of Huntington’s Disease Modifiers Using the Hyperbolic Mapping of the Protein Interaction Network

Huntington’s disease (HD) is caused by the production of a mutant huntingtin (HTT) with an abnormally long poly-glutamine (polyQ) tract, forming aggregates and inclusions in neurons. Previous work by us and others has shown that an increase or decrease in polyQ-triggered aggregates can be passive si...

Descripción completa

Detalles Bibliográficos
Autores principales: Vagiona, Aimilia-Christina, Mier, Pablo, Petrakis, Spyros, Andrade-Navarro, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144261/
https://www.ncbi.nlm.nih.gov/pubmed/35628660
http://dx.doi.org/10.3390/ijms23105853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9144261/
https://www.ncbi.nlm.nih.gov/pubmed/35628660
http://dx.doi.org/10.3390/ijms23105853

Ejemplares similares